In analgesic naive horses with chronic laminitis co administration of tramadol and ketamine resulted in significant improvement in off loading frequency forelimb load and plasma levels of a major pro inflammatory cytokine and a critical vasoconstrictor prostanoid 3it is possible that co administration of tramadol with nsaids could result in greater mod ulation of inflammatory responses and superior pain management than when each drug is used alone. Tramadol oral tablets come in both. So many treatment modalities drugs and over the counter supplements are available that it becomes frustrating just to develop a plan based on solid science.
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